The project’s goal is to identify Adeno-associated virus (AAV) toxicity biomarkers in vitro using cutting-edge spatial proteomics methods.
AAV is a tiny parvovirus with a capsid that can be modified to operate as a vector delivery system for gene therapy or to enable in vivo biologic expression. In a small number of cases, the use of AAV-based therapeutics causes adverse effects (AE) in the clinic, including liver toxicity.
You will use a multi-omics strategy to assess AAV-cell interactions, employing unique spatial proteomics methods developed by Professor Kathryn Lilley’s lab (http://proteomics.bio.cam.ac.uk/) that precisely localize proteins to subcellular structures on a proteome-wide scale.
About the Scholarship:
The University of Cambridge is the world’s second-oldest university and is regarded as one of the top five universities in the world. The Russell Group, a network of research-focused British universities; the Coimbra Group, an organization of premier European universities; the League of European Research Universities; and the International Alliance of Research Universities are all members of the University. It is also considered to be a component of the “Golden Triangle,” a geographical cluster of top research universities. To date, Cambridge has produced 89 Nobel laureates, the most of any university, and Trinity College alone has produced more Nobel laureates than France. After the Queen and the Church of England, the University of Cambridge is the third largest landowner in the country. Cambridge, being a collegiate university, is unique in that it has no campus, instead consisting of 31 self-governing colleges united under the Cambridge umbrella. Each college is a part of Cambridge while remaining mostly autonomous. They designate their own teaching staff and fellows in each discipline, decide which students to admission, supervise undergraduate teaching, and are responsible for the domestic arrangements and welfare of students and staff. Choosing the appropriate institution is critical, not just to ensure the student gets a spot, but also to ensure the degree is successful. Students’ main point of contact is their college, which has a variety of orientation options. Student societies and voluntary alumni groups also offer assistance, hosting fresher parties throughout September to introduce students to one another and university life. At the start of each academic year, the International Student Team hosts an orientation event to provide information about the university as well as the opportunity to meet other international students. International students at the University of Cambridge are likewise represented by the iCSU. New international students are welcomed as soon as they arrive in the city, and social events are planned throughout the year. Cambridge now has 1,300 international students from 65 nations enrolled.
Accommodation is provided by each college on an individual basis and varies greatly. Most colleges possess houses and flats in Cambridge, but they can also provide undergraduates with accommodation for all three years of study. The Accommodation Service can also assist with arranging private rental accommodation in the town. Cambridge is a significant town in Cambridgeshire, approximately 80 kilometers north of London. The university buildings, which have been a part of the town’s history for over 800 years, dominate the area. Cambridge is a small city, and nearly all of the colleges and departments are in close proximity to one another. They are linked by a bus service, and Cambridge is known for being one of the most bicycle-friendly cities in the country. The thirty-one colleges are mostly independent of the university and have a lot of freedom. Colleges have the authority to choose which students to admit and to designate their own “senior members,” or professors. Stansted, Luton, Heathrow, and Gatwick are the four major airports that serve Cambridge. All four airports have National Express coach connections to Cambridge, as well as direct trains from London that take roughly an hour. Cambridge University is made up of several institutions, with the university’s primary functions distributed between the university’s central departments and university colleges. Each department is in charge of doing research and delivering centralized lectures to Cambridge students in general. The general welfare and domestic management of all students and some university workers are the responsibility of university colleges. The majority of small group teaching for undergraduates, known as tutorial supervisions, is also provided by colleges. Cambridge is steeped in history, and its world-famous colleges and university structures draw tourists from all over the globe. However, the University’s museums and collections contain many gems that provide an interesting glimpse into some of the University’s professors and students’ scholarly endeavors, both past and present. The university’s Cambridge University Press is the world’s oldest publishing house and the world’s second-largest university press.
It employs about 11,000 people and operates 31 colleges, as well as 150 departments, faculties, schools, and other organizations. The University has an international community that invites brilliant students from all around the world. The university currently has over 20,000 undergraduate and postgraduate students, as well as around 9,000 international students from over 140 other countries. Around 25% of undergraduate students and 50% of graduate students are from outside the United Kingdom.
Scholarship Sponsor(s): University of Cambridge
Scholarship Country: United Kingdom
Scholarship Worth: £17500
Study Level: Postgraduate
Nationality: International Students
For up to four years, a stipend (now around £17500) will be granted. This financing covers the University Composition Fee (Home Fee Rate) as well as maintenance and consumables.
Eligibility for Scholarship.
UK citizens or EU students who meet the UK residency requirements for Home fees, as well as international (including EU) candidates who can provide the difference in Home and Overseas costs from other sources, are eligible for the studentship.
The University of Cambridge MRC PhD Studentships 2022 is open to all International Students
- To apply, please send the following information to Prof. Lilley (firstname.lastname@example.org) by March 18, 2022: CV (maximum of two pages) with full contact information for two academic referees and a covering letter (maximum of two pages) summarizing (a) your research interests, (b) what you aim to achieve from the program, (c) your career objectives, and (d) why you want to do this PhD.
- Please apply to the University using the Applicant Portal by the deadline listed above: http://www.graduate.study.cam.ac.uk/how-do-i-apply. Completed applications are required. Please look for “Biochemistry” PhD studentships in the Course Directory. Please note that the ‘Research Summary’ section of the University application form must be completed.
The application deadline for University of Cambridge MRC PhD Studentships 2022 is 18 March, 2022